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S100B modulates growth factors and costimulatory molecules expression in cultured human astrocytes

✍ Scribed by Camilla Reali; Rita Pillai; Francesca Saba; Stefano Cabras; Fabrizio Michetti; Valeria Sogos


Book ID
113730928
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
590 KB
Volume
243
Category
Article
ISSN
0165-5728

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## Abstract Astrocytes sense, integrate, and respond to stimuli generated by neurons or neural injury; this response involves gap junction (GJ) communication. Neuronal vulnerability to injury increased when cocultures of astrocytes and neurons were exposed to GJ inhibitors. However, GJ uncoupling c