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S-phase fraction and ploidy as predictive markers in primary disease and recurrence of papillary thyroid carcinoma

✍ Scribed by António E. Pinto; Giovani L. Silva; Teresa Pereira; Rafael A. Cabrera; Jorge Rosa Santos; Valeriano Leite

Book ID: 114720460
Publisher: John Wiley and Sons
Year: 2012
Tongue: English
Weight: 131 KB
Volume: 77
Category: Article
ISSN: 0300-0664
DOI: 10.1111/j.1365-2265.2012.04363.x

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## Abstract ## Background The value of flow cytometric analysis of DNA ploidy and S‐phase fraction (SPF) as an indicator of regional metastasis in oral cancer is currently being debated. Intratumoral heterogeneity makes this problem complex. ## Methods Intratumoral DNA ploidy heterogeneity and i