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S-(+)-aporphines are not selective for human D3dopamine receptors

✍ Scribed by Nora S. Kula; Ross J. Baldessarini; John W. Kebabian; John L. Neumeyer


Book ID
105458645
Publisher
Springer
Year
1994
Tongue
English
Weight
528 KB
Volume
14
Category
Article
ISSN
0272-4340

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L-dopa remains the most common treatment for Parkinson's disease. However, there is considerable interest in D3/D2 receptor agonists such as the novel agent S32504, since they exert antiparkinsonian properties in the absence of dyskinesia. An important question concerns the roles of D2 vs. D3 recept