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S-Adenosylmethionine (SAMe) ameliorates taurolithocholate (TLC) induced cholestasis in the rat

✍ Scribed by Schölmerich, J.; Baumgartner, U.; Reinhardt, M.; Gerok, W.


Book ID
122941361
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
118 KB
Volume
11
Category
Article
ISSN
0168-8278

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Tauroursodeoxycholate and S-adenosyl-L-m
✍ Piotr Milkiewicz; Charles O. Mills; Marcelo G. Roma; Jalal Ahmed-Choudhury; Elwy 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 125 KB

The monohydroxy bile acid, taurolithocholate (TLC), causes cholestasis in vivo and in isolated perfused livers. It is also cholestatic in vitro and, in this study using isolated rat hepatocyte couplets, causes a reduction of the accumulation of (fluorescent) bile acid in the canalicular vacuoles (cV