S-adenosylmethionine decarboxylase gene expression is regulated by the cAMP signal transduction pathway in H-ras transformed fibrosarcoma cells capable of malignant progression

Growth factor-mediated altered expressio

Growth factor-mediated altered expression and regulation of S-adenosylmethionine decarboxylase in a H-ras transformed cell line capable of malignant progression

✍ Marcus S. Hardin; Robert A. R. Hurta 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 207 KB 👁 2 views

## Abstract Mammalian S‐adenosylmethionine decarboxylase (SAMDC) is a regulatory activity, which is involved in the biosynthesis of polyamines. The polyamines, namely putrescine, spermidine, and spermine, are essential for mammalian cell proliferation. SAMDC expression was examined in a H‐ras trans