S-adenosylhomocysteine is associated with subclinical atherosclerosis and renal function in a cardiovascular low-risk population
✍ Scribed by Zawada, Adam M.; Rogacev, Kyrill S.; Hummel, Björn; Berg, Judith T.; Friedrich, Annika; Roth, Heinz J.; Obeid, Rima; Geisel, Jürgen; Fliser, Danilo; Heine, Gunnar H.
- Book ID
- 121819459
- Publisher
- Elsevier Science
- Year
- 2014
- Tongue
- English
- Weight
- 661 KB
- Volume
- 234
- Category
- Article
- ISSN
- 0021-9150
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## Abstract ## Objective Atherosclerosis is the most common pathologic process underlying cardiovascular disease (CVD). It is not well known whether subclinical atherosclerosis is an independent risk factor for lower cognitive function among individuals without clinically evident CVD. ## Methods
Oxidative stress plays an important role in the development of atherosclerosis. Excess visceral adipose tissue (VAT) and increased carotid intima-media thickness (IMT) are risk factors for coronary artery disease. We tested the hypothesis that VAT and IMT were associated with systemic oxidative stre