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S-adenosyl-l-methionine protection against α-naphthyl- isothiocyanate-induced cholestasis in the rat

✍ Scribed by Di Padovaa, Carlo; Di Padova, Franco; Tritapepe, Raffaele; Stramentinoli, Giorgio


Book ID
122724003
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
425 KB
Volume
29
Category
Article
ISSN
0378-4274

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The monohydroxy bile acid, taurolithocholate (TLC), causes cholestasis in vivo and in isolated perfused livers. It is also cholestatic in vitro and, in this study using isolated rat hepatocyte couplets, causes a reduction of the accumulation of (fluorescent) bile acid in the canalicular vacuoles (cV