𝔖 Bobbio Scriptorium
✦   LIBER   ✦

(S)-3-[(R)-2,4-Dimethylpent-4-enoyl]-4-isopropyl-5,5-diphenyl-1,3-oxazolidin-2-one

✍ Scribed by Tannert, René ;Schürmann, Markus ;Preut, Hans ;Arndt, Hans-Dieter ;Waldmann, Herbert

Publisher
International Union of Crystallography
Year
2007
Tongue
English
Weight
335 KB
Volume
63
Category
Article
ISSN
1600-5368

No coin nor oath required. For personal study only.

✦ Synopsis

The title compound, C~25~H~29~NO~3~, was prepared in the course of the generation of depsipeptide libraries resembling the Jasplakinolide family of natural products. The dihedral angle between the phenyl ring planes is 74.1 (3)° The oxazolidinone ring adopts a slightly distorted ^4^
E conformation with an axial projection of the isopropyl substituent, which is easily rationalized by pseudo-allylic strain exerted by the exocyclic imide carbonyl. The two carbonyl groups adopt a noncolinear S-shaped conformation.

📜 SIMILAR VOLUMES

(4R,5R)-1,3-Dimethyl-4,5-diphenyl­imidaz
(4R,5R)-1,3-Dimethyl-4,5-diphenyl­imidazolidin-2-one
✍ Kawahata, Masatoshi ;Saito, Noriko ;Ishikawa, Tsutomu ;Yamaguchi, Kentaro 📂 Article 📅 2006 🏛 International Union of Crystallography 🌐 English ⚖ 127 KB

The title compound, C 17 H 18 N 2 O, was obtained by methylation of (4R,5R)-4,5-diphenylimidazolidin-2-one. The C-O bond exhibits double-bond character, and both C-N bonds in the urea group are intermediate between single and double bonds.

(+)-(4R,5S)-4-Methyl-5-phenyl-3-[2(S)-ph
(+)-(4R,5S)-4-Methyl-5-phenyl-3-[2(S)-phenyl­propion­yl]oxazolidin-2-one
✍ Coumbarides, Gregory S. ;Eames, Jason ;Motevalli, Majid ;Malatesti, Nela ;Yohann 📂 Article 📅 2006 🏛 International Union of Crystallography 🌐 English ⚖ 223 KB

In the title compound, C 19 H 19 NO 3 , formed from enantiomerically pure (+)-(4R,5S)-4-methyl-5-phenyl-2-oxazolidinone and racemic 2-phenylpropanoyl chloride, the two carbonyl groups are oriented anti to each other, and the two methyl groups are oriented anti to each other.