(S)-2,3,5,10,11,11a-Hexahydro-1H-pyrrolo[2,1-c][1,4]benzodiazepine-3,11-dione
β Scribed by Cheng, Mao-Sheng ;Ma, Chao ;Liu, Jing-Hong ;Sha, Yu ;Wang, Qing-He
- Publisher
- International Union of Crystallography
- Year
- 2007
- Tongue
- English
- Weight
- 627 KB
- Volume
- 63
- Category
- Article
- ISSN
- 1600-5368
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π SIMILAR VOLUMES
The molecule of the title compound, C~26~H~30~N~2~O~4~S, adopts a folded conformation, with the sulfonyl-bound benzene ring lying over the pyridinone ring [centroid-to-centroid distance = 3.893β (1)β Γ ], forming a dihedral angle of 23.87β (5)Β°. The pyrrolidine ring adopts a twist conformation and the d
The asymmetric unit of the title compound, C 26 H 30 N 2 O 4 S, consists of two independent molecules, A and B, with similar conformations. In both molecules, the pyrrolidine and dihydropyran rings adopt envelope conformations, and are trans-fused; the tosyl group is attached to the pyrrolidine ring
## Abstract magnified image Efficient synthesis of biological important pyrrolo[2,1β__c__][1,4]benzodiazepineβ5,11βdione dimer linked through the Cβ2 positions by fumarate group is described.