๐”– Bobbio Scriptorium
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S-1: a promising new oral fluoropyrimidine derivative

โœ Scribed by Saif, Muhammad Wasif; Syrigos, Kostas N; Katirtzoglou, Nikos A

Book ID
121419874
Publisher
Informa plc
Year
2009
Tongue
English
Weight
464 KB
Volume
18
Category
Article
ISSN
1354-3784

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Capecitabine (Xeloda) ยฎ was developed as a tumour-selective fluoropyrimidine carbamate to achieve higher intratumoural 5-FU level and lower toxicity than 5-FU. Capecitabine passes unchanged through the gastrointestinal tract and is metabolised in the liver to 5%-deoxy-5-fluorocytidine (5%-DFCR). Her