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Ryanodine Receptor Recruitment and Construction of Calcium Release Sites in Cardiac Myocytes

✍ Scribed by Zahradnikova, Alexandra; Janicek, Radoslav; Zahradnikova, Alexandra; Gaburjakova, Marta; Zahradnik, Ivan

Book ID: 122926567
Publisher: Biophysical Society
Year: 2012
Tongue: English
Weight: 42 KB
Volume: 102
Category: Article
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2011.11.1739

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## Abstract The cardiac ryanodine receptor (RyR2), the major calcium release channel on the sarcoplasmic reticulum (SR) in cardiomyocytes, has recently been shown to be involved in at least two forms of sudden cardiac death (SCD): (1) Catecholaminergic polymorphic ventricular tachycardia (CPVT) or