Ryanodine- and thapsigargin-insensitive Ca2+-induced Ca2+release is primed by lowering external Ca2+in rabbit autonomic neurons

Involvement of endoplasmic reticulum Ca2

Involvement of endoplasmic reticulum Ca2+ release through ryanodine and inositol 1,4,5-triphosphate receptors in the neurotoxic effects induced by the amyloid-β peptide

✍ Elisabete Ferreiro; Catarina R. Oliveira; Cláudia Pereira 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 133 KB

## Abstract Studies with in‐vitro‐cultured neurons treated with amyloid‐β (Aβ) peptides demonstrated neuronal loss by apoptosis that is due, at least in part, to the perturbation of intracellular Ca^2+^ homeostasis. In addition, it was shown that an endoplasmic reticulum (ER)‐specific apoptotic pat