Ruthenium-catalyzed ring closing olefin metathesis of non-natural α-amino acids

✍ Scribed by Floris P.J.T. Rutjes; Hans E. Schoemaker

• Book ID: 104256136
• Publisher: Elsevier Science
• Year: 1997
• Tongue: French
• Weight: 255 KB
• Volume: 38
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(96)02390-8

✦ Synopsis

The use of various enantiopure amino acid-derived diolefins as substrates for the ring closing olefin metathesis reaction (RCM) has been investigated. This reaction has been shown to be an efficient transformation for providing highly functionalized 6-and 7-membered ring amino acids.