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Ruthenium-catalyzed oxidation of β-lactams with molecular oxygen and aldehydes
✍ Scribed by Shun-Ichi Murahash; Takao Saito; Takeshi Naota; Hidenori Kumobayashi; Susumu Akutagawa
- Book ID
- 104216014
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- French
- Weight
- 269 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0040-4039
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📜 SIMILAR VOLUMES
Osmium-catalyzed oxidation of klactams with peroxides in acetic acid gives the corresponding 4-acetoxy B-lactams, which are versatile synthetic intermediate of carbapenem antibiotics, in good to excellent yields. Oxidation of p-lactams is of importance in view of synthesis of carbapenem and thiopen
A variety of aromatic and some aliphatic aldehydes are efficientlv transformed to the corresvondinq carboxvlic acid in presence of catalytic amount of Cobal: (II)-chloride, molecular oxyyen and acetic anhydride at room temperature. Phenolic aldehydes underyo acylatiue oxidation to give the correspon