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Ruthenium-catalyzed enyne metathesis in stereoselective preparation of cyclic 1-amino-1-carboxylic acids

โœ Scribed by Kristin Hammer; Kjell Undheim


Book ID
104207949
Publisher
Elsevier Science
Year
1997
Tongue
French
Weight
701 KB
Volume
53
Category
Article
ISSN
0040-4020

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Ruthenium(II) in ring closing metathesis
โœ Kristin Hammer; Kjell Undheim ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 844 KB

Stereoselective synthesis of or-amino acids where the s-carbon of the amino acid is incorporated into a five-, six-or seven-membered ring is described. The stereoselective control results from stepwise bisalkenylation of (R)-2,5-dihydro-3,6-dimethoxy-2-isopropylpyrazine. Ring closing metathesis was