Ruthenium catalyzed asymmetric hydrogenation of α- and β-keto esters in ionic liquids using chiral P-Phos ligand
✍ Scribed by Lam, Kim Hung; Xu, Lijin; Feng, Lichun; Ruan, Jiwu; Fan, Qinghua; Chan, Albert SC
- Book ID
- 120505979
- Publisher
- NRC Research Press
- Year
- 2005
- Tongue
- French
- Weight
- 73 KB
- Volume
- 83
- Category
- Article
- ISSN
- 0008-4042
- DOI
- 10.1139/v05-102
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The applications of the chiral dipyridylphosphine ligand P-Phos and its derivatives Tol-P-Phos and Xyl-P-Phos in Ruand Rh-catalyzed hydrogenations of the methyl esters of a variety of (Z)-2-acetamido-3-arylacrylic acids have been studied systematically. The results show that the electronic and steri
A new chiral dipyridylphosphine ligand Xyl-P-Phos has been synthesized and the structure of (S)-Xyl-P-Phos oxide has been characterized by single crystal X-ray diffraction. The ruthenium complex of this ligand, Ru(R-Xyl-P-Phos)(C 6 H 6 )Cl 2 , has been found to be a highly active, enantioselective a