Ruth Bishop: rotaviruses and vaccines
โ Scribed by Amanda Tattam
- Book ID
- 117294520
- Publisher
- The Lancet
- Year
- 1999
- Tongue
- English
- Weight
- 52 KB
- Volume
- 353
- Category
- Article
- ISSN
- 0140-6736
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Candidate vaccines against rotavirus-caused diarrhoea have been under development for more than ten years. Recent research has helped to identify virological and immunological parameters which are most likely to be correlates of protection from rotavirus infection and disease. Large double-blind, pl
Sixteen specimens of faeces from children with acute diarrhoea due to rotavirus were inoculated into MA-104 cells. Rotaviruses present in six of the specimens were successfully adapted to growth after serial passage. Two of these strains had "short RNA" patterns and had caused epidemics of diarrhoea