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RUNX2 expression in developing human bones and various bone tumors

✍ Scribed by Masato Sugawara; Noriko Kato; Takashi Tsuchiya; Teiichi Motoyama

Book ID
115176339
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
923 KB
Volume
61
Category
Article
ISSN
1320-5463

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Signaling networks in RUNX2-dependent bo
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✍ Toshihisa Komori πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 English βš– 110 KB

## Abstract RUNX2 is an essential transcription factor for osteoblast differentiation and chondrocyte maturation. SP7, another transcription factor, is required for osteoblast differentiation. Major signaling pathways, including FGF, Wnt, and IHH, also play important roles in skeletal development.