Runx2/Cbfa1, but not loss of myocardin,
โ
Mei Y. Speer; Xianwu Li; Pranoti G. Hiremath; Cecilia M. Giachelli
๐
Article
๐
2010
๐
John Wiley and Sons
๐
English
โ 727 KB
## Abstract Vascular calcification is a major risk factor for cardiovascular morbidity and mortality. Smooth muscle cells (SMCs) may play an important role in vascular cartilaginous metaplasia and calcification via reprogramming to the osteochondrogenic state. To study whether SM lineage reprogramm