RuII-SDP-Complex-Catalyzed Asymmetric Hydrogenation of Ketones. Effect of the Alkali Metal Cation in the Reaction.
β Scribed by Jian-Hua Xie; Sheng Liu; Xiang-Hong Huo; Xu Cheng; Hai-Feng Duan; Bao-Ming Fan; Li-Xin Wang; Qi-Lin Zhou
- Publisher
- John Wiley and Sons
- Year
- 2005
- Weight
- 40 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0931-7597
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## Abstract The chiral amino amide **3** was derived from Lβproline and used for the [RuCl~2~(__p__βcymene)]~2~βcatalyzed asymmetric transfer hydrogenation of prochiral ketones performed in water. Moderate to good chemical selectivities (up to 95% yield) and enantioselectivities (up to 90% ee) were