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Ru(II)-Pheox catalyzed N–H insertion reaction of diazoacetamides: synthesis of N-substituted α-aminoamides

✍ Scribed by Soda Chanthamath; Songkharm Thongjareun; Kazutaka Shibatomi; Seiji Iwasa


Book ID
116909711
Publisher
Elsevier Science
Year
2012
Tongue
French
Weight
773 KB
Volume
53
Category
Article
ISSN
0040-4039

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## Abstract Rh~2~(4__S__‐MEOX)~4~ and ethereal solvent are the best catalytic system for the enantioselective intramolecular C–H insertion of __N__‐(2‐benzyloxyethyl)‐__N__‐(__tert__‐butyl)diazoacetamide **2**. The highest enantiomeric excess obtained was 91%. A new route for the asymmetric synthes