✦ LIBER ✦

Rubella-associated aplastic anemia treated by syngeneic stem cell transplantations

✍ Scribed by Hoon Kook; Geun Mo Kim; Hyeoung Joon Kim; Chan Jong Kim; Won Sang Yoon; Tai Ju Hwang

Publisher: John Wiley and Sons
Year: 2000
Tongue: English
Weight: 29 KB
Volume: 64
Category: Article
ISSN: 0361-8609
DOI: 10.1002/1096-8652(200008)64:4<303::aid-ajh11>3.0.co;2-0

No coin nor oath required. For personal study only.

✦ Synopsis

A 14-year-old boy presented with aplastic anemia 3 months after contracting rubella. Stem cell transplantations from his identical twin were carried out. Successful engraftment occurred only when conditioning therapy was given prior to the infusion of the syngeneic stem cells, supporting an immune mechanism to explain the pathogenesis of virus-associated aplastic anemia.