Ru-MCM-41 catalysts for diastereoselective hydrogenation

✍ Scribed by M Florea; M Sevinci; V.I Pârvulescu; G Lemay; S Kaliaguine

• Book ID: 104430383
• Publisher: Elsevier Science
• Year: 2001
• Tongue: English
• Weight: 241 KB
• Volume: 44-45
• Category: Article
• ISSN: 1387-1811
• DOI: 10.1016/s1387-1811(01)00224-4

✦ Synopsis

Ru-MCM-41 catalysts were prepared by deposition of several complexes from their solvents: of Ru acetylacetonate from its ether solution, of cis-dichlorobis(2,2 H -bipyridine) Ru in chloroform, of di-lchlorobis((p-cymene)chloro Ru(II)) in chloroform and of dichloro(1,5-cyclooctadiene) Ru(II) dissolved in pyridine. The catalysts were characterized as prepared and after several reactions cycles by: adsorption±desorption isotherms of N 2 at 77 K, XRD, FTIR, and XPS. The above catalysts were used in the liquid phase hydrogenation of a F prostaglandin intermediate. A strong leaching of Ru was observed, but after four cycles the catalysts remained unchanged in activity and diastereoselectivity. The stereoselectivity was found to be in¯uenced by the nature of the precursor complex. In the presence of the catalyst prepared from di-lchlorobis((p-cymene)chloro Ru(II)) the natural-like product was obtained.