RTI-352: A 3α analogue of RTI-55 as an in vivo dopamine transporter binding ligand

Long-lasting inhibition of in vivo cocai

Long-lasting inhibition of in vivo cocaine binding to dopamine transporters by 3β-(4-Iodophenyl)Tropane-2-Carboxylic acid Methyl Ester: RTI-55 or βCIT

✍ Dr. N. D. Volkow; S. J. Gatley; J. S. Fowler; R. Chen; J. Logan; S. L. Dewey; Y. 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 642 KB

Cocaine analogs such as 3~-(4-iodophenyl)tropane-2~-carboxylic acid methyl ester (RTI-55 or PCIT) with a higher affinity for the dopamine transporter (DAT) may be potentially useful in interfering with cocaine's actions in brain. This study evaluates the time course of the effects of RTI-55 on cocai