✦ LIBER ✦

RTI-113 administration reduces cocaine self-administration at high occupancy of dopamine transporter

✍ Scribed by Steven I. Dworkin; Philip Lambert; Glen M. Sizemore; F. Ivy Carroll; Michael J. Kuhar

Book ID: 101267698
Publisher: John Wiley and Sons
Year: 1998
Tongue: English
Weight: 125 KB
Volume: 30
Category: Article
ISSN: 0887-4476
DOI: 10.1002/(sici)1098-2396(199809)30:1<49::aid-syn6>3.0.co;2-k

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✦ Synopsis

tropan-2␤ carboxylic acid phenyl ester hydrochloride], one of many phenyltropanes potent at and selective for DAT, inhibited self-administration of cocaine in rat at doses that did not alter responding maintained by food. The doses that inhibited cocaine intake produced significant levels of occupancy of DAT. Synapse 30:49-55, 1998.

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