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RS 86 in the treatment of alzheimer's disease: Cognitive and biological effects

✍ Scribed by Eric Hollander; Michael Davidson; Richard C. Mohs; Thomas B. Horvath; Bonnie M. Davis; Zvi Zemishlany; Kenneth L. Davis


Book ID
118317497
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
939 KB
Volume
22
Category
Article
ISSN
0006-3223

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The muscarinic agonist RS 86 was administered to patients with Alzheimer's disease (AD) and senile dementia of the Alzheimer type (SDAT) in a series of controlled clinical trials. Daily doses were up to 3.0 mg orally for a maximum duration of 18 weeks. RS 86 produced typical peripheral cholinergic e