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RPA involvement in the damage-recognition and incision steps of nucleotide excision repair

✍ Scribed by He, Zhigang; Henricksen, Leigh A.; Wold, Marc S.; Ingles, C. James

Book ID
109791646
Publisher
Nature Publishing Group
Year
1995
Tongue
English
Weight
492 KB
Volume
374
Category
Article
ISSN
0028-0836

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Critical DNA damage recognition function
Critical DNA damage recognition functions of XPC-hHR23B and XPA-RPA in nucleotide excision repair
✍ Brian S. Thoma; Karen M. Vasquez πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 270 KB

## Abstract It has been reported that 80–90% of human cancers may result, in part, from DNA damage. Cell survival depends critically on the stability of our DNA and exquisitely sensitive DNA repair mechanisms have developed as a result. In humans, nucleotide excision repair (NER) protects the DNA a