Elevated basal reactive oxygen species a
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Brent D. Butts; Kevin A. Kwei; G. Tim Bowden; Margaret M. Briehl
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Article
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2003
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John Wiley and Sons
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English
β 158 KB
Resistance to apoptosis may be a critical phenotype that cells must acquire during skin carcinogenesis. The Akt kinase is a known upstream regulator of apoptosis in many cell types and has been shown to be activated by increased reactive oxygen species (ROS). We have previously demonstrated that two