✍ Scribed by D. Du T. Rossouw
No coin nor oath required. For personal study only.
An existing method, developed in our laboratory, has been further improved for the large scale routine production of [mI]mlBG. Losses of 1231 during production have been decreased from 16% to <3% and labelling efficiencies of >98% are now consistently obtained. A sensitive HPLC quality control method for p23I]mlBG, based on reversephase ion-pair chromatography, has also been developed.
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This paper presents strategies for an automated control of distortion at the operational level of a production process chain, as well as first steps towards a combined implementation in heat-treatment processes. In order to minimise the loss of production due to quality defects, the first quality co