Routes to pyrrolo[2,1-b]thiazoles. Rotational isomerism of pyrrolo[2,1-b]thiazole-5-carbaldehydes
β Scribed by Brindley, Jocelyn C.; Gillon, David G.; Meakins, G. Denis
- Book ID
- 120791190
- Publisher
- Royal Society of Chemistry
- Year
- 1986
- Weight
- 551 KB
- Category
- Article
- ISSN
- 1472-7781
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π SIMILAR VOLUMES
AMrae&-2,6-Dimethylpyrrolo[2,I-b)]thiaxole, 8, undergoes electrophilic substitution with dimethyl acetylenedicarboxylate to form the cb-and trans-5-dicarbomethoxyvinyl derivatives of 8. With tetracyanoethylene as electrophile, 5-and 'I-tricyanovinyl derivatives of 8 are formed. Butyllithium metalate
## Abstract A modular synthesis of selectivelyβsubstituted pyrrolo[2,1β__b__]thiazoles (Ξ^6^ isomeric form) has been implemented, involving a distinctive bicyclization reaction of a mucobromic acid derivative followed by a SuzukiβMiyaura coupling. A novel process of Ξ^6^ to Ξ^7^ isomerization of th
## Abstract For Abstract see ChemInform Abstract in Full Text.