✦ LIBER ✦
Rotational isomerism in 3-mono-oxygenated and 3,7-di-oxygenated derivatives of N-acetyl-17-aza-D-homoandrost-5-ene
✍ Scribed by Philip J. Dawson; Trevor A. Crabb; Roger O. Williams
- Publisher
- John Wiley and Sons
- Year
- 1977
- Tongue
- English
- Weight
- 359 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0749-1581
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
The ^1^H n.m.r. spectra of 3‐mono‐oxygenated and 3,7‐dioxygenated N‐acetyl‐17‐aza‐D‐homoandrost‐5‐enes show unequal populations of the amide rotational isomers in chloroform‐d~1~ solution. The populations are dependent upon the orientation of the C‐7 oxygen substituent but are independent of concentration. In pyridine‐d~5~ solution the two rotameric states for each compound are almost equally populated.