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Rosuvastatin is a high affinity substrate of hepatic organic anion transporter OATP-C

✍ Scribed by Brown, C.D.A.; Windass, A.; Bleasby, K.; Lauffart, B.


Book ID
118630312
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
174 KB
Volume
2
Category
Article
ISSN
1567-5688

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πŸ“œ SIMILAR VOLUMES


Organic anion–transporting polypeptide 1
✍ IvΓ‘n L. Csanaky; Hong Lu; Youcai Zhang; Kenichiro Ogura; Supratim Choudhuri; Cur πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 713 KB

The organic anion-transporting polypeptide 1b family (Oatp1b2 in rodents and OATP1B1/1B3 in humans) is liver-specific and transports various chemicals into the liver. However, the role of the Oatp1b family in the hepatic uptake of bile acids (BAs) into the liver is unknown. Therefore, in Oatp1b2-nul