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Rosuvastatin ameliorates high-fat and high-cholesterol diet-induced nonalcoholic steatohepatitis in rats

✍ Scribed by Okada, Yoshihisa; Yamaguchi, Kanji; Nakajima, Tomoki; Nishikawa, Taichiroh; Jo, Masayasu; Mitsumoto, Yasuhide; Kimura, Hiroyuki; Nishimura, Takeshi; Tochiki, Nozomi; Yasui, Kohichiroh; Mitsuyoshi, Hironori; Minami, Masahito; Kagawa, Keizo; Okanoue, Takeshi; Itoh, Yoshito

Book ID
119878618
Publisher
John Wiley and Sons
Year
2013
Tongue
English
Weight
860 KB
Volume
33
Category
Article
ISSN
0106-9543

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## Abstract It has been suggested that patients with nonalcoholic steatohepatitis (NASH) may have high risk for liver cancer. However, it is unknown whether high‐fat diet (HFD) induced NASH promotes hepatocarcinogenesis. In this study, Sprague‐Dawley rats were injected with a low dose of hepatic ca