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Rosmarinic acid down-regulates endothelial protein C receptor shedding in vitro and in vivo

✍ Scribed by Ku, Sae-Kwang; Yang, Eun-Ju; Song, Kyung-Sik; Bae, Jong-Sup


Book ID
123473120
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
713 KB
Volume
59
Category
Article
ISSN
0278-6915

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## Abstract Both __Tbx1__ and retinoic acid (RA) are key players in embryonic pharyngeal development; loss of __Tbx1__ produces DiGeorge syndrome‐like phenotypes in mouse models as does disruption of retinoic acid homeostasis. We have demonstrated that perturbation of retinoic acid levels in the av