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Rosiglitazone reduces cell invasiveness by inducing MKP-1 in human U87MG glioma cells

✍ Scribed by Hsun-Jin Jan; Chin-Cheng Lee; Yu-Min Lin; Jing-Huei Lai; Hen-Wei Wei; Horng-Mo Lee

Book ID
116335078
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
591 KB
Volume
277
Category
Article
ISSN
0304-3835

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## Abstract The immediate early response gene IEX‐1 is involved in the regulation of apoptosis and cell growth. In order to increase the apoptotic sensitivity to chemotherapeutic drugs and γ‐ray, we attempted to establish U87‐MG human glioma cell line expressing IEX‐1. Unexpectedly, however, transf