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Rosiglitazone for Nonalcoholic Steatohepatitis: One-Year Results of the Randomized Placebo-Controlled Fatty Liver Improvement With Rosiglitazone Therapy (FLIRT) Trial

✍ Scribed by Vlad Ratziu; Philippe Giral; Sophie Jacqueminet; Fréderic Charlotte; Agnès Hartemann–Heurtier; Lawrence Serfaty; Philippe Podevin; Jean–Marc Lacorte; Carole Bernhardt; Eric Bruckert; André Grimaldi; Thierry Poynard


Book ID
119760374
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
479 KB
Volume
135
Category
Article
ISSN
0016-5085

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Short-term trials of glitazones in nonalcoholic steatohepatitis (NASH) yielded controversial histological results. Longer treatment might result in additional improvement. After a 1-year randomized trial, 53 patients underwent a control liver biopsy and were enrolled in an open-label extension trial