✦ LIBER ✦

ROS-NFκΒ mediates TGF-β1-induced expression of urokinase-type plasminogen activator, matrix metalloproteinase-9 and cell invasion

✍ Scribed by Nicolas Tobar; Victor Villar; Juan F. Santibanez

Publisher: Springer
Year: 2010
Tongue: English
Weight: 488 KB
Volume: 340
Category: Article
ISSN: 0300-8177
DOI: 10.1007/s11010-010-0418-5

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

TGF-β–induced invasiveness of pancreatic

TGF-β–induced invasiveness of pancreatic cancer cells is mediated by matrix metalloproteinase-2 and the urokinase plasminogen activator system

✍ Volker Ellenrieder; Sandra F. Hendler; Claudia Ruhland; Wolfgang Boeck; Guido Ad 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 French ⚖ 216 KB

TGF-beta strongly promotes local tumor progression in advanced epithelial tumors, though the underlying mechanisms are poorly understood. In the present study, we demonstrate the potential of TGF-beta to increase the invasiveness of the pancreatic cancer cell lines PANC-1 and IMIM-PC1. TGF-beta-indu

Spred2 inhibits TGF-β1-induced urokinase

Spred2 inhibits TGF-β1-induced urokinase type plasminogen activator expression, cell motility and epithelial mesenchymal transition

✍ Victor Villar; Jelena Kocić; Juan F. Santibanez 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 French ⚖ 460 KB 👁 1 views

## Abstract TGF‐β1 is a potent inductor of malignance in cancer cells. TGF‐β1 stimulates the expression of extracellular matrix degrading proteases, cell migration and it is also involved in the epithelial‐mesenchymal transition (EMT). In the present work, we analyzed the role of Spred2 in the urok

FGF-1-induced matrix metalloproteinase-9

FGF-1-induced matrix metalloproteinase-9 expression in breast cancer cells is mediated by increased activities of NF-κB and activating protein-1

✍ Gina Lungu; Lina Covaleda; Odete Mendes; Heidi Martini-Stoica; George Stoica 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 365 KB

## Abstract Matrix metalloproteinase‐9 (MMP‐9) plays a critical role in tumor invasion and metastasis. Here, we investigate the effect of fibroblast growth factor‐1 (FGF‐1) on the expression of MMP‐9 in ENU1564, an ethyl‐__N__‐nitrosourea‐induced rat mammary adenocarcinoma cell line. We observed th

Slug is a downstream mediator of transfo

Slug is a downstream mediator of transforming growth factor-β1-induced matrix metalloproteinase-9 expression and invasion of oral cancer cells

✍ Mathew J. Joseph; Surabhi Dangi-Garimella; Mario A. Shields; Michelle E. Diamond 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 361 KB 👁 1 views

## Abstract Members of Snail family of transcription factors play an important role in oral cancer progression by inducing epithelial–mesenchymal transition, by promoting invasion and by increasing matrix metalloproteinase (MMP) expression. Although Snail (Snai1) is the best characterized and the m

ERK1/2 mediates TNF-α-induced matrix met

ERK1/2 mediates TNF-α-induced matrix metalloproteinase-9 expression in human vascular smooth muscle cells via the regulation of NF-κB and AP-1: Involvement of the ras dependent pathway

✍ Sung-Kwon Moon; Byung-Yoon Cha; Cheorl-Ho Kim 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 386 KB 👁 1 views

## Abstract The expression of matrix metalloproteinase‐9 (MMP‐9) has been implicated in progression of atherosclerotic lesions. The role and importance of the signaling pathway in the transcriptional regulation of MMP‐9 in human aortic smooth muscle cells (HASMC) was examined. Tumor necrosis factor