## Abstract The molecular basis for the pharmacologic effects of __N__β(4βhydroxyphenyl)retinamide (4HPR) was investigated by studying the gene(s) that this compound may upregulate in cultured human epithelial tumor cells. Treatment of the cultured human nasopharyngeal carcinomaβderived cells (CNE3
ROS mediates 4HPR-induced posttranscriptional expression of the Gadd153 gene
β Scribed by Wai-Lung Lai; Nai-Sum Wong
- Book ID
- 113629549
- Publisher
- Elsevier Science
- Year
- 2005
- Tongue
- English
- Weight
- 504 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0891-5849
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## Abstract The transcription factor Sp1 plays an important regulatory role in transactivation of the lung type I cell differentiation gene __T1Ξ±__. Like other lung cells, type I cells may encounter changes in oxygen concentration during the lifetime of the organism. We found that exposure of mice