Ropren® is a polyprenol preparation from coniferous plants that ameliorates cognitive deficiency in a rat model of beta-amyloid peptide-(25–35)-induced amnesia

Dicholine salt of succinic acid, a neuro

Dicholine salt of succinic acid, a neuronal insulin sensitizer, ameliorates cognitive deficits in rodent models of normal aging, chronic cerebral hypoperfusion, and beta-amyloid peptide-(25–35)-induced amnesia

✍ Zinaida I Storozheva; Andrey T Proshin; Vladimir V Sherstnev; Tatiana P Storozhe 📂 Article 📅 2008 🏛 BioMed Central 🌐 English ⚖ 368 KB

## Background Accumulated evidence suggests that insulin resistance and impairments in cerebral insulin receptor signaling may contribute to age-related cognitive deficits and Alzheimer's disease. The enhancement of insulin receptor signaling is, therefore, a promising strategy for the treatment of