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Root stimulation improves the detection of acquired demyelinating polyneuropathies

✍ Scribed by Daniel L. Menkes; Daniel C. Hood; Roderick A. Ballesteros; David A. Williams

Publisher: John Wiley and Sons
Year: 1998
Tongue: English
Weight: 138 KB
Volume: 21
Category: Article
ISSN: 0148-639X
DOI: 10.1002/(sici)1097-4598(199803)21:3<298::aid-mus3>3.0.co;2-5

No coin nor oath required. For personal study only.

✦ Synopsis

Thirty-one patients with a presentation compatible with an acquired demyelinating polyradiculoneuropathy were prospectively evaluated for proximal conduction block using root stimulation (RS) of cervical and/or lumbar roots. These same techniques were applied to 78 controls (40 pathological). Proximal conduction block was noted in 20/31 cases and none of the controls. Only 7 of 31 cases met published demyelinating criteria. Intravenous immune globulin therapy was completed by 21/31 patients and 20/21 responded. RS is superior to published electrophysiologic criteria for identifying demyelinating polyneuropathies and predicting who will respond to treatment. RS should be performed in all patients suspected of having an acquired demyelinating polyneuropathy when traditional nerve conduction studies criteria are nondiagnostic. RS reliably predicts those likely to respond to immunosuppressive therapy.

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