Room temperature ionic liquid promoted synthesis of 1,5-benzodiazepine derivatives under ambient conditions

✍ Scribed by D.V Jarikote; S.A Siddiqui; R Rajagopal; Thomas Daniel; R.J Lahoti; K.V Srinivasan

• Book ID: 104253036
• Publisher: Elsevier Science
• Year: 2003
• Tongue: French
• Weight: 208 KB
• Volume: 44
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(03)00096-0

✦ Synopsis

The reaction of o-phenylenediamines with both acyclic and cyclic ketones in the ionic liquid 1,3-di-n-butylimidazolium bromide afforded 1,5-benzodiazepines in excellent isolated yields in the absence of a catalyst at ambient temperature.