Acute hypoxia increases intracellular L-
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Yunchao Su; Edward R. Block
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Article
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1996
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John Wiley and Sons
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English
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Exposure to hypoxia (0% O2) for 4-24 h resulted in increased intracellular L-arginine content and increased activity of calpain, a calcium-dependent neutral cysteine protease, in pulmonary artery endothelial cells. Calpain-inhibitor I abolished the increased L-arginine content in hypoxic cells. When