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Roles of TRAF6 in CD40 signaling

✍ Scribed by Bruce S. Hostager

Publisher
Springer-Verlag
Year
2007
Tongue
English
Weight
196 KB
Volume
39
Category
Article
ISSN
0257-277X

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## Abstract The CD40 receptor and the Epstein‐Barr virus oncoprotein LMP1 are both members of the TNF‐receptor family and share several signaling mediators, including TRAF2 and TRAF3. Depending on the cell lineage and stage of maturation, LMP1 and CD40 can have synergistic, antagonist or unrelated