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Roles of p38 MAPK and JNK in TGF-β1-induced Human Alveolar Epithelial to Mesenchymal Transition

✍ Scribed by Chen, Hai-hua; Zhou, Xian-long; Shi, Yu-lu; Yang, Jiong

Book ID
122558474
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
675 KB
Volume
44
Category
Article
ISSN
0188-4409

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## Abstract Idiopathic pulmonary fibrosis is characterized by myofibroblast accumulation, extracellular matrix (ECM) remodeling, and excessive collagen deposition. ECM‐producing myofibroblasts may originate from epithelial cells through epithelial to mesenchymal transition (EMT). TGF‐β1 is an induc