Roles of Nitric Oxide in Surgical Infection and Sepsis
✍ Scribed by Mark L. Johnson; Timothy R. Billiar
- Publisher
- Springer
- Year
- 1998
- Tongue
- English
- Weight
- 237 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0364-2313
No coin nor oath required. For personal study only.
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## Abstract Nitric oxide (NO) is a short‐living free molecule synthesized by three different isoforms of nitric oxide synthases (NOS)—neuronal NOS, endothelial NOS, and inducible NOS—associated with neuromuscular transmission, muscle contractility, mitochondrial respiration, and carbohydrate metabo
nder physiological conditions, nitric oxide (NO)-dependent signaling pathways function through different mechanisms involving the interaction with metal centers and the modification of proteins through amino acid residues. For example, the wellknown interaction of soluble guanylate cyclase with NO i