Roles of Host Gene and Non-coding RNA Expression in Virus Infection

✍ Scribed by Ralph A. Tripp, S. Mark Tompkins

Publisher: Springer International Publishing
Year: 2018
Tongue: English
Leaves: 283
Series: Current Topics in Microbiology and Immunology 419
Edition: 1st ed.
Category: Library

No coin nor oath required. For personal study only.

✦ Synopsis

This volume discusses the interactions between viruses and their host cells, and explores the roles of host and viral genes and non-coding RNAs in the virus replication cycle. During infection, viruses express a variety of genes, encoding proteins and RNAs that serve to subjugate the cell – by redirecting cellular processes to support viral replication and, at the same time, by mitigating the cellular response to infection. In this book, experts discuss these interactions in depth, and elaborate on our current understanding of virus-cell interactions for a diverse range of viruses, including positive and negative sense RNA viruses, DNA viruses, and a vector-borne virus. The roles of non-coding RNAs are also discussed. While each class of viruses has distinct replication requirements, this volume reveals unique features and commonalities in viral replication cycles. Accordingly, it represents a valuable source of information for researchers and clinicians alike.

✦ Table of Contents

Front Matter ....Pages i-vii
Host Factors in Coronavirus Replication (Adriaan H. de Wilde, Eric J. Snijder, Marjolein Kikkert, Martijn J. van Hemert)....Pages 1-42
Roles of Pro-viral Host Factors in Mosquito-Borne Flavivirus Infections (Rafael K. Campos, Mariano A. Garcia-Blanco, Shelton S. Bradrick)....Pages 43-67
Role of Innate Genes in HIV Replication (Kerstin Schott, Maximilian Riess, Renate König)....Pages 69-111
Host Factors Involved in Ebola Virus Replication (Angela L. Rasmussen)....Pages 113-150
Role of Host Genes in Influenza Virus Replication (Megan L. Shaw, Silke Stertz)....Pages 151-189
A Functional Genomics Approach to Henipavirus Research: The Role of Nuclear Proteins, MicroRNAs and Immune Regulators in Infection and Disease (Cameron R. Stewart, Celine Deffrasnes, Chwan Hong Foo, Andrew G. D. Bean, Lin-Fa Wang)....Pages 191-213
Roles of Non-coding RNAs in Respiratory Syncytial Virus (RSV) Infection (Ralph A. Tripp, Abhijeet A. Bakre)....Pages 215-241
Roles of Non-coding RNAs During Herpesvirus Infection (Meaghan H. Hancock, Rebecca L. Skalsky)....Pages 243-280

✦ Subjects

Biomedicine; Virology; Infectious Diseases

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