Recent studies suggest that the pathogenesis of HIV infection and AIDS involves two distinct phases. During acute infection, massive depletion of CD4 + CCR5 + memory T cells within the mucosal-associated lymphoid tissue leads to major and potentially irreversible damage to CD4 + T-cell-mediated immu
โฆ LIBER โฆ
Roles of HIV-1 auxiliary proteins in viral pathogenesis and host-pathogen interactions
โ Scribed by LI, Lin; LI, Hai Shan; PAUZA, C David; BUKRINSKY, Michael; ZHAO, Richard Y
- Book ID
- 110020698
- Publisher
- Nature Publishing Group
- Year
- 2005
- Tongue
- English
- Weight
- 458 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0007-0610
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## Abstract Human immunodeficiency virus typeโ1 particles contain host proteins, both on their surface and interior. This review summarises the cellular proteins found in these virions and covers some of their potential roles in the viral life cycle and pathogenesis. For most proteins studied, thei