𝔖 Bobbio Scriptorium
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Roles of fascin in human carcinoma motility and signaling: Prospects for a novel biomarker?

✍ Scribed by Yosuke Hashimoto; Marek Skacel; Josephine C. Adams


Book ID
116307019
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
369 KB
Volume
37
Category
Article
ISSN
1357-2725

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## Abstract In metastatic cancer, high expression levels of vitronectin (VN) receptors (integrins), FAK, and ERK5 are reported. We hypothesized that integrin‐mediated ERK5 activation via FAK may play a pivotal role in cell adhesion, motility, and metastasis. ERK5 and FAK phosphorylation when metast