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Roles of chromatin assembly factor 1 in the epigenetic control of chromatin plasticity

✍ Scribed by Hai Huang; RenJie Jiao

Book ID
107350020
Publisher
Science in China Press (SCP)
Year
2012
Tongue
English
Weight
412 KB
Volume
55
Category
Article
ISSN
1674-7305

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## Abstract The __SMARCA4__/__BRG1__ gene product is a component of the SWI‐SNF chromatin‐remodeling complex and regulates gene expression by disrupting histone‐DNA contacts in an ATP‐dependent manner. Inactivating mutations of the __SMARCA4__ gene, on chromosome arm 19p, are present in several hum