## Abstract Free radical nitric oxide (NO), generated by inducible nitric oxide synthase (iNOS) in astrocytes and macrophages, has been implicated in CNS inflammatory disorders such as multiple sclerosis and its animal model experimental autoimmune encephalomyelitis (EAE). Mycophenolic acid (MPA),
Roles for protein kinases in the induction of nitric oxide synthase in astrocytes
β Scribed by Martha L. Simmons; Dr. Sean Murphy
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- English
- Weight
- 956 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0894-1491
No coin nor oath required. For personal study only.
β¦ Synopsis
Lipopolysaccharide (LPS) or a combination of interferon (1FN)-y and interleukin (ILl-lp can induce a calcium-independent nitric oxide synthase (iNOS) in
π SIMILAR VOLUMES
A free radical, nitric oxide (NO), besides being a messenger molecule in the brain, becomes a neurotoxin if overproduced. We recently reported that methylmercury (MeHg) induces neuronal NO synthase (nNOS) in Purkinje cells. In the present study, we examined the distribution and the mechanism of nNOS
## Abstract Nitric oxide (NO) has been long recognized as an atypical neuronal messenger affecting excitatory synaptic transmission, but its cellular source has remained unresolved as the neuronal isoform of NO synthase (nNOS) in many brain regions is expressed only by small subsets of inhibitory n
## Abstract Waterβdeprivationβinduced osmotic stress leads to activation of a number of adaptive responses. Nitric oxide (NO) has been implicated in the modulation of these responses, as the amygdala has been implicated in ingestive behavior and modulation of autonomic homeostatic functions. Here w